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RESEARCH
Our innovation is driven by continuous investment in scientific research and discovery. We ensure the benefits of our products are rigorously studied, with every claim supported by a strong body of evidence — from ingredient to finished formula.
The result? Node doesn’t just feel different — its impact is measurable.
Node is built on ingredients with published scientific research selected for their demonstrated effects on brain health, cognitive performance, and neurological longevity across peer-reviewed studies and clinical trials.
Tested for impact on:
The brain consumes roughly 20% of the body's total energy while representing just 2% of its mass. That metabolic demand requires a constant supply of specific vitamins, minerals, and neuroactive compounds to maintain cognitive function.
Research shows that targeted nutritional supplementation can meaningfully support neurotransmitter synthesis, synaptic plasticity, and neuroprotection. Studies demonstrate that specific vitamin and mineral combinations improve methylation cycles that regulate memory, mood, and mental clarity. Nootropic compounds have been shown to enhance cholinergic memory pathways, support neuronal membrane integrity, and improve cerebrovascular circulation across peer-reviewed trials.
Cognitive Foundation brings 40 of these studied compounds into a single daily formula designed to deliver the foundational nutrition the brain requires to function at its best.
Chronic stress, inflammation, and age-related decline are among the most significant threats to long-term brain health. A growing body of research points to adaptogenic mushrooms as one of the most promising natural interventions for neural resilience and cognitive longevity.
Published studies show that specific medicinal mushrooms can stimulate nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), supporting neurogenesis and synaptic repair. Research demonstrates their role in modulating the HPA axis to reduce the neurotoxic effects of sustained cortisol exposure, enhancing cerebral oxygenation and mitochondrial energy production, and contributing anti-neuroinflammatory and antioxidant activity through naturally occurring beta-glucans and triterpenes.
Adaptogen Complex brings 10 of these studied mushrooms into a concentrated formula designed to support the brain's ability to adapt, recover, and perform over time.
Cognitive performance is not static. The brain's ability to focus, process, and perform fluctuates based on neurotransmitter availability, stress load, and energy metabolism. Research on neuroactive compounds has identified specific ingredients that can meaningfully shift these variables in real time.
Studies show that targeted amino acids, neuromodulators, and botanicals can enhance acetylcholine synthesis for faster processing and recall, promote alpha brain wave activity for focused and sustained energy, and replenish key neurotransmitters depleted under acute mental stress. Research also demonstrates a measurable blunting effect on cortisol under cognitive load, preserving mental clarity under pressure.
Accelerator Complex brings these studied compounds into a single targeted formula designed to deliver cognitive performance when it matters most.
There are many ways to study how nutrition affects the brain. Our formulas are informed by peer-reviewed research using advanced methodologies to explore the connection between targeted nutrient intake and cognitive function, neural resilience, and long-term brain health.
Daily System (30-Day Supply)
$2.62/serving
$104.97
PURCHASE INCLUDES:
Cognitive Foundation
Daily Vitamins & Minerals for Brain Health*
Included
Adaptogen Complex
Neural Resilience & Cognitive Adaptation*
Included
Accelerator Complex
On-Demand Focus & Cognitive Performance*
Included
You Pay
$78.73 per month
30-day money back guarantee
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Node products are shown to close common nutrient gaps and support brain health. We offer a once-a-day system that delivers a range of multivitamins, adaptogens, nootropics, amino acids, antioxidants, and more.
Node is designed to support brain health, sustained cognitive performance, and long-term vitality through a combination of essential nutrients, adaptogens, and neuroactive compounds.
Consistency matters most. While results can vary from person to person, many users begin noticing benefits within the first 30 days of daily use.
Node formulas deliver the best results when taken consistently. Daily use allows their benefits to compound over time.
Each serving of the Daily System (5 capsules total) provides a range of multivitamins, adaptogens, nootropics, amino acids, antioxidants, and more. We recommend taking 2 capsules of Cognitive Foundation, 2 capsules of Adaptogen Complex, and 1 capsule of Accelerator Complex daily, depending on your diet, or as directed by your healthcare provider.
We let you try your first Node order risk-free. You have 30 days to enjoy all the health benefits and make Node part of your daily routine. If you’re not completely satisfied, just email our Customer Success Team at support@nodeformulas.com to initiate the refund process.
You can reach out to our Customer Success Team by phone or email anytime. Head here for our support phone number and email address.
